Biomarkers of aging

It is also possible to predict the human chronological age using the [[transcriptomic clock]].<ref>{{cite journal | vauthors = Peters MJ, Joehanes R, Pilling LC, Schurmann C, Conneely KN, Powell J, Reinmaa E, Sutphin GL, Zhernakova A, Schramm K, Wilson YA, Kobes S, Tukiainen T, Nalls MA, Hernandez DG, Cookson MR, Gibbs RJ, Hardy J, Ramasamy A, Zonderman AB, Dillman A, Traynor B, Smith C, Longo DL, Trabzuni D, Troncoso J, van der Brug M, Weale ME, O’Brien R, Johnson R, Walker R, Zielke RH, Arepalli S, Ryten M, Singleton AB, Ramos YF, Göring HH, Fornage M, Liu Y, Gharib SA, Stranger BE, De Jager PL, Aviv A, Levy D, Murabito JM, Munson PJ, Huan T, Hofman A, Uitterlinden AG, Rivadeneira F, van Rooij J, Stolk L, Broer L, Verbiest MM, Jhamai M, Arp P, Metspalu A, Tserel L, Milani L, Samani NJ, Peterson P, Kasela S, Codd V, Peters A, Ward-Caviness CK, Herder C, Waldenberger M, Roden M, Singmann P, Zeilinger S, Illig T, Homuth G, Grabe HJ, Völzke H, Steil L, Kocher T, Murray A, Melzer D, Yaghootkar H, Bandinelli S, Moses EK, Kent JW, Curran JE, Johnson MP, Williams-Blangero S, Westra HJ, McRae AF, Smith JA, Kardia SL, Hovatta I, Perola M, Ripatti S, Salomaa V, Henders AK, Martin NG, Smith AK, Mehta D, Binder EB, Nylocks KM, Kennedy EM, Klengel T, Ding J, Suchy-Dicey AM, Enquobahrie DA, Brody J, Rotter JI, Chen YD, Houwing-Duistermaat J, Kloppenburg M, Slagboom PE, Helmer Q, den Hollander W, Bean S, Raj T, Bakhshi N, Wang QP, Oyston LJ, Psaty BM, Tracy RP, Montgomery GW, Turner ST, Blangero J, Meulenbelt I, Ressler KJ, Yang J, Franke L, Kettunen J, Visscher PM, Neely GG, Korstanje R, Hanson RL, Prokisch H, Ferrucci L, Esko T, Teumer A, van Meurs JB, Johnson AD | title = The transcriptional landscape of age in human peripheral blood | journal = Nature Communications | volume = 6 | issue = 1 | article-number = 8570 | date = 22 October 2015 | pmid = 26490707 | pmc = 4639797 | doi = 10.1038/ncomms9570 | bibcode = 2015NatCo…6.8570. }}</ref>

It is also possible to predict the human chronological age using the [[transcriptomic clock]].<ref>{{cite journal | vauthors = Peters MJ, Joehanes R, Pilling LC, Schurmann C, Conneely KN, Powell J, Reinmaa E, Sutphin GL, Zhernakova A, Schramm K, Wilson YA, Kobes S, Tukiainen T, Nalls MA, Hernandez DG, Cookson MR, Gibbs RJ, Hardy J, Ramasamy A, Zonderman AB, Dillman A, Traynor B, Smith C, Longo DL, Trabzuni D, Troncoso J, van der Brug M, Weale ME, O’Brien R, Johnson R, Walker R, Zielke RH, Arepalli S, Ryten M, Singleton AB, Ramos YF, Göring HH, Fornage M, Liu Y, Gharib SA, Stranger BE, De Jager PL, Aviv A, Levy D, Murabito JM, Munson PJ, Huan T, Hofman A, Uitterlinden AG, Rivadeneira F, van Rooij J, Stolk L, Broer L, Verbiest MM, Jhamai M, Arp P, Metspalu A, Tserel L, Milani L, Samani NJ, Peterson P, Kasela S, Codd V, Peters A, Ward-Caviness CK, Herder C, Waldenberger M, Roden M, Singmann P, Zeilinger S, Illig T, Homuth G, Grabe HJ, Völzke H, Steil L, Kocher T, Murray A, Melzer D, Yaghootkar H, Bandinelli S, Moses EK, Kent JW, Curran JE, Johnson MP, Williams-Blangero S, Westra HJ, McRae AF, Smith JA, Kardia SL, Hovatta I, Perola M, Ripatti S, Salomaa V, Henders AK, Martin NG, Smith AK, Mehta D, Binder EB, Nylocks KM, Kennedy EM, Klengel T, Ding J, Suchy-Dicey AM, Enquobahrie DA, Brody J, Rotter JI, Chen YD, Houwing-Duistermaat J, Kloppenburg M, Slagboom PE, Helmer Q, den Hollander W, Bean S, Raj T, Bakhshi N, Wang QP, Oyston LJ, Psaty BM, Tracy RP, Montgomery GW, Turner ST, Blangero J, Meulenbelt I, Ressler KJ, Yang J, Franke L, Kettunen J, Visscher PM, Neely GG, Korstanje R, Hanson RL, Prokisch H, Ferrucci L, Esko T, Teumer A, van Meurs JB, Johnson AD | title = The transcriptional landscape of age in human peripheral blood | journal = Nature Communications | volume = 6 | issue = 1 | article-number = 8570 | date = 22 October 2015 | pmid = 26490707 | pmc = 4639797 | doi = 10.1038/ncomms9570 | bibcode = 2015NatCo…6.8570. }}</ref>

== Epigenetic marks ==

== Epigenetic ==

=== Loss of histones ===

=== Loss of histones ===