”’Adiponectin receptor 1”’ (”’AdipoR1”’) is a [[protein]] which in humans is encoded by the ”ADIPOR1” [[gene]].<ref name=”pmid12802337″>{{cite journal | vauthors = Yamauchi T, Kamon J, Ito Y, Tsuchida A, Yokomizo T, Kita S, Sugiyama T, Miyagishi M, Hara K, Tsunoda M, Murakami K, Ohteki T, Uchida S, Takekawa S, Waki H, Tsuno NH, Shibata Y, Terauchi Y, Froguel P, Tobe K, Koyasu S, Taira K, Kitamura T, Shimizu T, Nagai R, Kadowaki T | title = Cloning of adiponectin receptors that mediate antidiabetic metabolic effects | journal = Nature | volume = 423 | issue = 6941 | pages = 762–9 | date = June 2003 | pmid = 12802337 | doi = 10.1038/nature01705 | bibcode = 2003Natur.423..762Y | s2cid = 52860797 }}</ref> It is a member of the [[progestin and adipoQ receptor]] (PAQR) family, and is also known as ”’PAQR1”’.<ref name=”TangHu2005″>{{cite journal | vauthors = Tang YT, Hu T, Arterburn M, Boyle B, Bright JM, Emtage PC, Funk WD | title = PAQR proteins: a novel membrane receptor family defined by an ancient 7-transmembrane pass motif | journal = Journal of Molecular Evolution | volume = 61 | issue = 3 | pages = 372–80 | date = September 2005 | pmid = 16044242 | doi = 10.1007/s00239-004-0375-2 | bibcode = 2005JMolE..61..372T | s2cid = 31473802 }}</ref>
”’Adiponectin receptor 1”’ (”’AdipoR1”’) is a [[protein]] which in humans is encoded by the ”ADIPOR1” [[gene]].<ref name=”pmid12802337″>{{cite journal | vauthors = Yamauchi T, Kamon J, Ito Y, Tsuchida A, Yokomizo T, Kita S, Sugiyama T, Miyagishi M, Hara K, Tsunoda M, Murakami K, Ohteki T, Uchida S, Takekawa S, Waki H, Tsuno NH, Shibata Y, Terauchi Y, Froguel P, Tobe K, Koyasu S, Taira K, Kitamura T, Shimizu T, Nagai R, Kadowaki T | title = Cloning of adiponectin receptors that mediate antidiabetic metabolic effects | journal = Nature | volume = 423 | issue = 6941 | pages = 762–9 | date = June 2003 | pmid = 12802337 | doi = 10.1038/nature01705 | bibcode = 2003Natur.423..762Y | s2cid = 52860797 }}</ref> It is a member of the [[progestin and adipoQ receptor]] (PAQR) family, and is also known as ”’PAQR1”’.<ref name=”TangHu2005″>{{cite journal | vauthors = Tang YT, Hu T, Arterburn M, Boyle B, Bright JM, Emtage PC, Funk WD | title = PAQR proteins: a novel membrane receptor family defined by an ancient 7-transmembrane pass motif | journal = Journal of Molecular Evolution | volume = 61 | issue = 3 | pages = 372–80 | date = September 2005 | pmid = 16044242 | doi = 10.1007/s00239-004-0375-2 | bibcode = 2005JMolE..61..372T | s2cid = 31473802 }}</ref>
The [[adiponectin receptor]]s, AdipoR1 and [[AdipoR2]], serve as receptors for globular and full-length [[adiponectin]] and mediate increased [[AMP-activated protein kinase|AMPK]] and [[Peroxisome proliferator-activated receptor alpha|PPAR-α]] ligand activities, as well as [[fatty acid]] oxidation and glucose uptake by adiponectin.<ref name=”pmid12802337″/><ref name=”entrez”>{{cite web | title = Entrez Gene: ADIPOR1 adiponectin receptor 1| url = https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=51094}}</ref> In 2016, the University of Tokyo announced that it would launch an investigation into claims of fabrication of AdipoR1 and AdipoR2 identification data, as accused by an anonymous person/group called [[Ordinary_researchers]].<ref name=”Dennis”>[https://www.science.org/content/article/university-tokyo-investigate-data-manipulation-charges-against-six-prominent-research University of Tokyo to investigate data manipulation charges against six prominent research groups] ScienceInsider, Dennis Normile, Sep 20, 2016</ref>
The [[adiponectin receptor]]s, AdipoR1 and [[AdipoR2]], serve as receptors for globular and full-length [[adiponectin]] and mediate increased [[AMP-activated protein kinase|AMPK]] and [[Peroxisome proliferator-activated receptor alpha|PPAR-α]] ligand activities, as well as [[fatty acid]] oxidation and glucose uptake by adiponectin.<ref name=”pmid12802337″/><ref name=”entrez”>{{cite web | title = Entrez Gene: ADIPOR1 adiponectin receptor 1| url = https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=51094}}</ref> In 2016, the University of Tokyo announced that it would launch an investigation into claims of fabrication of AdipoR1 and AdipoR2 identification data, as accused by an anonymous person/group called [[]].<ref name=”Dennis”>[https://www.science.org/content/article/university-tokyo-investigate-data-manipulation-charges-against-six-prominent-research University of Tokyo to investigate data manipulation charges against six prominent research groups] ScienceInsider, Dennis Normile, Sep 20, 2016</ref>
