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Latest revision as of 10:45, 30 January 2026
Pharmaceutical compound
Stattic is a drug that acts as an inhibitor of the transcription factor protein STAT3. It has potential applications in the treatment of cancer and autoimmune disorders.[1][2][3]
- ^ Ko HJ, Kim YJ. Signal transducer and activator of transcription proteins: regulators of myeloid-derived suppressor cell-mediated immunosuppression in cancer. Arch Pharm Res. 2016 Nov;39(11):1597-1608. doi:10.1007/s12272-016-0822-9 PMID 27572156
- ^ Samad MA, Ahmad I, Hasan A, Alhashmi MH, Ayub A, Al-Abbasi FA, Kumer A, Tabrez S. STAT3 Signaling Pathway in Health and Disease. MedComm (2020). 2025 Mar 30;6(4):e70152. doi:10.1002/mco2.70152 PMID 40166646
- ^ Wu Z, Lian G, He L, Hu P, Guo Y, Su Z. Targeting JAK-STAT signaling for autoimmune diseases: current understanding, clinical advances, and emerging directions. Immunol Cell Biol. 2026 Jan 9. doi:10.1111/imcb.70078 PMID 41517955
