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{{Short description|Medical condition of skeletal muscles}} |
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”’Zenker’s degeneration”’ is a severe glassy or waxy [[hyaline]] [[Degeneration (medical)|degeneration]] or [[necrosis]] of [[skeleton|skeletal]] muscles in acute infectious diseases; a prototype of coagulative necrosis. |
”’Zenker’s degeneration”’ is a severe glassy or waxy [[hyaline]] [[Degeneration (medical)|degeneration]] or [[necrosis]] of [[skeleton|skeletal]] muscles in acute infectious diseases; a prototype of coagulative necrosis. |
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Latest revision as of 11:27, 5 October 2025
Medical condition of skeletal muscles
Zenker’s degeneration is a severe glassy or waxy hyaline degeneration or necrosis of skeletal muscles in acute infectious diseases; a prototype of coagulative necrosis.
The condition was named by Friedrich Albert von Zenker. It is a hyaline degeneration of skeletal muscles such as rectus abdominis and diaphragm, and occurs in severe toxaemia as typhoid fever. It is also seen in electrical burns.[1] Grossly the muscles appear pale and friable; microscopically, the muscle fibres are swollen, have a loss of cross striations, and show a hyaline appearance. Rupture and small hemorrhage may complicate the lesion. Coagulative necrosis occurs here.
