Cyclohexane-1,2-diol dehydrogenase: Difference between revisions

 

Line 8: Line 8:

| caption =

| caption =

}}

}}

In [[enzymology]], a ”’cyclohexane-1,2-diol dehydrogenase”’ ({{EC number|1.1.1.174}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

In [[enzymology]], ”’cyclohexane-1,2-diol dehydrogenase”’ ({{EC number|1.1.1.174}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

{{chemrxn|width=50%|

:trans-cyclohexane-1,2-diol + NAD⁺ <math>\rightleftharpoons</math> 2-hydroxycyclohexan-1-one + NADH + H⁺

{{chemrxn/cpd|qid=Q27102137|caption=[[Cyclohexane-1,2-diol|”trans”-cyclohexane-1,2-diol]]}}

{{chemrxn/txt|+ [[NAD+|NAD⁺]]}}

{{chemrxn/arw|direction=reversible|fwd_out={{chem2|H+}}|rev_in={{chem2|H+}} }}

{{chemrxn/cpd|qid=Q27102692|caption=[[2-hydroxycyclohexan-1-one]] }}

{{chemrxn/txt|+ [[NADH]]}}

}}

Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[trans-cyclohexane-1,2-diol]] and [[nicotinamide adenine dinucleotide|NAD⁺]], whereas its 3 [[product (chemistry)|products]] are [[2-hydroxycyclohexan-1-one]], [[nicotinamide adenine dinucleotide|NADH]], and [[hydrogen ion|H⁺]].

two [[substrate (biochemistry)|substrates]] of this enzyme are trans-cyclohexane-1,2-diol and [[nicotinamide adenine dinucleotideNAD⁺ [[product (chemistry)|products]] are 2-hydroxycyclohexan-1-one, NADH, and [[ |<><>.

This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The [[List of enzymes|systematic name]] of this enzyme class is ”’trans-cyclohexane-1,2-diol:NAD⁺ 1-oxidoreductase”’. This enzyme participates in [[caprolactam degradation]].

This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The [[List of enzymes|systematic name]] of this enzyme class is ”’trans-cyclohexane-1,2-diol:NAD⁺ 1-oxidoreductase”’. This enzyme participates in [[caprolactam degradation]].

==References==

==References==

{{reflist|1}}

{{reflist}}

* {{cite journal |vauthors=Davey JF, Trudgill PW | date = 1977 | title = The metabolism of trans-cyclohexan-1,2-diol by an ”Acinetobacter” species | journal = Eur. J. Biochem. | volume = 74 | pages = 115&ndash;27 | pmid = 856571 | doi = 10.1111/j.1432-1033.1977.tb11373.x | issue = 1 | doi-access = free }}

{{Alcohol oxidoreductases}}

{{Alcohol oxidoreductases}}