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== Affiliated Companies == |
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Royan Institute has facilitated the creation of spin-off companies focused on regenerative medicine and biotechnology, such as Royan Stem Cell Technology Company and Cell Tech Pharmed Company, which develop cell-based therapies and biomedical products.<ref>{{cite journal |last1=Zarghami |first1=N. |title=Biotechnology startups in Iran: Challenges and opportunities |journal=Journal of Biotechnology |year=2021 |volume=339 |issue=2 |pages=56–62 |doi=10.1016/j.jbiotec.2021.07.012 |pmid=34352345}}</ref><ref>Saberi S, Karamzadeh R, Moghadam P, Kadivari M, Eghbal Behbahani B, Heydari Z, et al. “Research performance in stem cell science and regenerative medicine in Iran: a national comprehensive observation.” Arch Iran Med. 2019;22(6):318-327, p. 323. https://www.researchgate.net/publication/334771327_Research_Performance_in_Stem_Cell_Science_and_Regenerative_Medicine_in_Iran_A_National_Comprehensive_Observation |
Royan Institute has facilitated the creation of spin-off companies focused on regenerative medicine and biotechnology, such as Royan Stem Cell Technology Company and Cell Tech Pharmed Company, which develop cell-based therapies and biomedical products.<ref>{{cite journal |last1=Zarghami |first1=N. |title=Biotechnology startups in Iran: Challenges and opportunities |journal=Journal of Biotechnology |year=2021 |volume=339 |issue=2 |pages=56–62 |doi=10.1016/j.jbiotec.2021.07.012 |pmid=34352345}}</ref> |
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<ref>Saberi S, Karamzadeh R, Moghadam P, Kadivari M, Eghbal Behbahani B, Heydari Z, et al. “Research performance in stem cell science and regenerative medicine in Iran: a national comprehensive observation.” Arch Iran Med. 2019;22(6):318-327, p. 323. https://www.researchgate.net/publication/334771327_Research_Performance_in_Stem_Cell_Science_and_Regenerative_Medicine_in_Iran_A_National_Comprehensive_Observation |
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Revision as of 08:20, 17 December 2025
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Iranian biomedical and stem cell research institute
Royan Institute
Royan Institute (Persian: پژوهشگاه رویان) is an Iranian public and non-governmental research institute in Tehran, Iran, operating under the Academic Center for Education, Culture and Research (ACECR) [1]. Founded in 1991 by Saeid Kazemi Ashtiani, it conducts research in reproductive biomedicine, stem cell biology, and developmental biotechnology.[2]
The institute began its activities with a primary focus on treating infertility and conducting research in reproductive biomedicine. Its scope of research later broadened to include stem cells and developmental biology. The Royan Institute is organized into several research divisions, including departments of stem cells, reproductive biotechnology, and animal biotechnology. It also operates specialized clinics aligned with its research areas.
Research Activities
The institute conducts research in three primary areas: reproductive biomedicine, stem cell biology, and developmental biotechnology. It has published extensively in peer-reviewed journals and holds several patents in biomedical technologies.[3][4] Royan collaborates with national and international research institutions and publishes two peer-reviewed journals: Cell Journal and International Journal of Fertility and Sterility.[5][6][7]
Scientific Milestones
- 2003: Established the first human embryonic stem cell (hESC) line in Iran and the Middle East.[8]
Research Divisions
Royan Institute operates three main divisions.[12][13]
Reproductive Biomedicine Institute: Conducts research in infertility treatment, reproductive genetics, endocrinology, and embryology
Stem Cell Biology and Technology: Conducts research in stem cell science and cell-based therapies.[14][3]
Developmental Biotechnology: Conducts research in developmental biology and biotechnology applications.[5]
Affiliated Companies
Royan Institute has facilitated the creation of spin-off companies focused on regenerative medicine and biotechnology, such as Royan Stem Cell Technology Company and Cell Tech Pharmed Company, which develop cell-based therapies and biomedical products.[15][16]
[17]
Advanced Therapy Medicinal Products (ATMP) Center
Since 2018, the Royan ATMP-Technology Development Center has focused on developing cell-based medicinal products in compliance with Good Manufacturing Practice (GMP) standards.[3]
See Also
References
- ^ “Iran holds Royan int’l scientific festival”. Islamic Republic News Agency (ISNA). 31 August 2016.
- ^ Rousseaux, S. (2014). “Two decades of reproductive biomedicine and stem cell biology in Iran: the Royan Institute”. International Journal of Developmental Biology. 58 (9). p. 644, col. 2, para. 2. doi:10.1387/ijdb.140245sr. PMID 25896200.
- ^ a b c Baharvand, Hossein; Hassani, Niloofar (2025). “Recent advances in cell-based therapies in Iran”. Regenerative Therapy. 42: 101–110. doi:10.1016/j.reth.2025.06.017. PMC 12274769. PMID 40689373.
- ^ Saberi, S.; Karamzadeh, R.; Moghadam, P.; Kadivari, M.; Eghbal Behbahani, B.; Heydari, Z.; Baharvand, H.; Aminpour, F.; Vosough, M. (2019). “Research performance in stem cell science and regenerative medicine in Iran”. Cell Journal. 22 (6): 318–327. doi:10.22074/cellj.2021.7001 (inactive 27 October 2025). PMID 31356098.
{{cite journal}}: CS1 maint: DOI inactive as of October 2025 (link) - ^ a b Cite error: The named reference
rousseaux2014was invoked but never defined (see the help page). - ^ “Cell Journal”. Retrieved 27 October 2025.
- ^ “International Journal of Fertility and Sterility”. Retrieved 27 October 2025.
- ^ Bahrami, S.; Hassani, S. (2003). “Establishment and in vitro differentiation of a new embryonic stem cell line from human blastocyst”. Stem Cells and Development. 12 (4): 431–438. doi:10.1590/s0100-879×2003000900011. PMID 12937788.
- ^ Nasr-Esfahani, M.; Hosseini, S. (2007). “Cloning and developmental competence of sheep embryos”. Reproduction, Fertility and Development. 19 (1): 201–207. doi:10.2131/jts.31.471. PMID 17202761.
- ^ https://www.researchgate.net/publication/266408867_Royana_Successful_Experience_in_Cloning_the_Sheep
- ^ Tait, Robert (7 August 2006). “Iranian scientists clone sheep”. The Guardian.
- ^ Rousseaux, S. (2014). “Two decades of reproductive biomedicine and stem cell biology in Iran: the Royan Institute”. Int J Dev Biol. 58 (9): 643–647. doi:10.1387/ijdb.140245sr. PMID 25896200.
- ^ Baharvand, Hossein; Gourabi, Hamid; Jafary, Hamideh; Totonchi, Mehdi (2010). “Stem Cell Research in the Islamic Republic of Iran”. Dialectical Anthropology. 34 (3): 706–707. doi:10.1111/j.1541-1338.2010.00467.x.
- ^ “46 papers from a Royan Institute professor”. 12 November 2020.
- ^ Zarghami, N. (2021). “Biotechnology startups in Iran: Challenges and opportunities”. Journal of Biotechnology. 339 (2): 56–62. doi:10.1016/j.jbiotec.2021.07.012. PMID 34352345.
- ^ “Stem Cell Research and Therapy in the Islamic Republic of Iran: Pioneering in the Islamic World”. ResearchGate. p. 6. Retrieved 17 December 2025.
- ^ Saberi S, Karamzadeh R, Moghadam P, Kadivari M, Eghbal Behbahani B, Heydari Z, et al. “Research performance in stem cell science and regenerative medicine in Iran: a national comprehensive observation.” Arch Iran Med. 2019;22(6):318-327, p. 323. https://www.researchgate.net/publication/334771327_Research_Performance_in_Stem_Cell_Science_and_Regenerative_Medicine_in_Iran_A_National_Comprehensive_Observation




