| [[Copa Airlines]] | [[Austin–Bergstrom International Airport|Austin]],<ref>{{cite web|title=4 new routes announced for Austin airport, including 2 new international destinations|url=https://www.kxan.com/news/local/austin/4-new-routes-announced-for-austin-airport-including-2-new-international-destinations/amp/|website=Kxan Austin|date=13 February 2023|access-date=13 February 2023}}</ref> [[Baltimore/Washington International Airport|Baltimore]],<ref>{{cite web|url=https://thedailyrecord.com/2023/01/26/copa-airlines-adds-bwi-to-north-american-route-schedule/|title=Copa Airlines adds BWI to North American route schedule |work= [[The Daily Record (Maryland)|The Daily Record]] |location= Baltimore, Maryland, USA |date= 26 January 2023 }}</ref> [[Hercílio Luz International Airport|Florianópolis]],<ref>{{cite web|title=Copa Airlines anuncia 3 destinos hacia México, Brasil y EEUU|url=https://www.ecotvpanama.com/economia/copa-airlines-anuncia-3-destinos-mexico-brasil-y-eeuu-n5964648|website=EcoTVPanama|date=5 February 2024|access-date=5 February 2024|language=es}}</ref> [[Eloy Alfaro International Airport|Manta]],<ref>{{cite web | url=https://www.nlarenas.com/2023/01/copa-airlines-anuncia-vuelos-panama-manta/ | title=Copa Airlines anuncia vuelos entre Panamá y Manta | date=26 January 2023 }}</ref> [[Salgado Filho Porto Alegre International Airport|Porto Alegre]],<ref>{{cite web|url=https://diariogaucho.clicrbs.com.br/dia-a-dia/noticia/2024/08/saiba-quais-sao-as-rotas-e-os-voos-ja-confirmados-para-a-volta-do-aeroporto-salgado-filho-em-outubro-cm05f94og010o015i9ho90ydu.html|title=Saiba quais são as rotas e os voos já confirmados para a volta do aeroporto Salgado Filho em outubro|website=Diário gaúcho|date=22 August 2024|access-date=17 October 2024|language=pt}}</ref> [[Gregorio Luperón International Airport|Puerto Plata]] (begins 13 January 2026),<ref>{{cite web |title=Copa Airlines Adds Puerto Plata to Its Route Network in Dominican Republic |url=https://aviacionaldia.com/en/2025/07/copa-airlines-adds-puerto-plata-to-its-route-network-in-dominican-republic.html |website=Aviación al Día |access-date=10 July 2025}}</ref> [[Raleigh–Durham International Airport|Raleigh/Durham]],<ref>{{cite web|title=Hola, Central America! Copa Airlines to fly direct from RDU to Panama|url=https://www.cbs17.com/news/local-news/wake-county-news/copa-airlines-nonstop-flight-raleigh-durham-international-airport-panama-city-panama-central-america/|website=CBS17|date=5 February 2024|access-date=5 February 2024}}</ref> [[Martín Miguel de Güemes International Airport|Salta]],{{cn|date=December 2025}} [[Salvador Bahia Airport|Salvador da Bahia]] (resumes 7 January 2026),<ref>{{cite web|url=https://aeroin.net/copa-airlines-tera-voo-do-panama-para-salvador-a-partir-de-janeiro/|title=Copa Airlines terá voo do Panamá para Salvador a partir de janeiro|website=Aeroin|date=3 July 2025|access-date=3 July 2025|language=pt}}</ref> [[San Diego International Airport|San Diego]],<ref>{{Cite web |last= |first= |date=25 February 2025 |title=Nonstop flights to Panama to begin from San Diego Airport this June |url=https://www.nbcsandiego.com/news/local/nonstop-flights-to-panama-to-begin-from-san-diego-airport-this-june/3763202/?amp=1 |access-date=25 February 2025 |website=NBC 7 San Diego |language=en-US}}</ref> [[Los Cabos International Airport|San José del Cabo]],<ref name=”panrotas.com.br”>{{cite web|url=https://www.panrotas.com.br/aviacao/empresas/2025/07/copa-airlines-anuncia-tres-novas-rotas-para-america-latina_219199.html|title=Copa Airlines anuncia três novas rotas para América Latina|website=Panrotas|date=3 July 2025|access-date=3 July 2025|language=pt}}</ref> [[Cibao International Airport|Santiago de los Caballeros]] (resumes 15 January 2026),<ref name=”panrotas.com.br”>{{cite web|url=https://www.panrotas.com.br/aviacao/empresas/2025/07/copa-airlines-anuncia-tres-novas-rotas-para-america-latina_219199.html|title=Copa Airlines anuncia três novas rotas para América Latina|website=Panrotas|date=3 July 2025|access-date=3 July 2025|language=pt}}</ref> [[Princess Juliana International Airport|Sint Maarten]],<ref>{{OAGWorldJuly2025Ref|title=St. Maarten, St Maarten (Dutch Part) SXM|pages=1000-1000}}</ref> [[Teniente General Benjamín Matienzo International Airport|Tucumán]]{{cn|date=December 2025}}
| [[Copa Airlines]] | [[Austin–Bergstrom International Airport|Austin]],<ref>{{cite web|title=4 new routes announced for Austin airport, including 2 new international destinations|url=https://www.kxan.com/news/local/austin/4-new-routes-announced-for-austin-airport-including-2-new-international-destinations/amp/|website=Kxan Austin|date=13 February 2023|access-date=13 February 2023}}</ref> [[Baltimore/Washington International Airport|Baltimore]],<ref>{{cite web|url=https://thedailyrecord.com/2023/01/26/copa-airlines-adds-bwi-to-north-american-route-schedule/|title=Copa Airlines adds BWI to North American route schedule |work= [[The Daily Record (Maryland)|The Daily Record]] |location= Baltimore, Maryland, USA |date= 26 January 2023 }}</ref> [[Hercílio Luz International Airport|Florianópolis]],<ref>{{cite web|title=Copa Airlines anuncia 3 destinos hacia México, Brasil y EEUU|url=https://www.ecotvpanama.com/economia/copa-airlines-anuncia-3-destinos-mexico-brasil-y-eeuu-n5964648|website=EcoTVPanama|date=5 February 2024|access-date=5 February 2024|language=es}}</ref> [[Eloy Alfaro International Airport|Manta]],<ref>{{cite web | url=https://www.nlarenas.com/2023/01/copa-airlines-anuncia-vuelos-panama-manta/ | title=Copa Airlines anuncia vuelos entre Panamá y Manta | date=26 January 2023 }}</ref> [[Salgado Filho Porto Alegre International Airport|Porto Alegre]],<ref>{{cite web|url=https://diariogaucho.clicrbs.com.br/dia-a-dia/noticia/2024/08/saiba-quais-sao-as-rotas-e-os-voos-ja-confirmados-para-a-volta-do-aeroporto-salgado-filho-em-outubro-cm05f94og010o015i9ho90ydu.html|title=Saiba quais são as rotas e os voos já confirmados para a volta do aeroporto Salgado Filho em outubro|website=Diário gaúcho|date=22 August 2024|access-date=17 October 2024|language=pt}}</ref> [[Gregorio Luperón International Airport|Puerto Plata]] (begins 13 January 2026),<ref>{{cite web |title=Copa Airlines Adds Puerto Plata to Its Route Network in Dominican Republic |url=https://aviacionaldia.com/en/2025/07/copa-airlines-adds-puerto-plata-to-its-route-network-in-dominican-republic.html |website=Aviación al Día |access-date=10 July 2025}}</ref> [[Raleigh–Durham International Airport|Raleigh/Durham]],<ref>{{cite web|title=Hola, Central America! Copa Airlines to fly direct from RDU to Panama|url=https://www.cbs17.com/news/local-news/wake-county-news/copa-airlines-nonstop-flight-raleigh-durham-international-airport-panama-city-panama-central-america/|website=CBS17|date=5 February 2024|access-date=5 February 2024}}</ref> [[Martín Miguel de Güemes International Airport|Salta]],{{cn|date=December 2025}} [[Salvador Bahia Airport|Salvador da Bahia]] (resumes 7 January 2026),<ref>{{cite web|url=https://aeroin.net/copa-airlines-tera-voo-do-panama-para-salvador-a-partir-de-janeiro/|title=Copa Airlines terá voo do Panamá para Salvador a partir de janeiro|website=Aeroin|date=3 July 2025|access-date=3 July 2025|language=pt}}</ref> [[San Diego International Airport|San Diego]],<ref>{{Cite web |last= |first= |date=25 February 2025 |title=Nonstop flights to Panama to begin from San Diego Airport this June |url=https://www.nbcsandiego.com/news/local/nonstop-flights-to-panama-to-begin-from-san-diego-airport-this-june/3763202/?amp=1 |access-date=25 February 2025 |website=NBC 7 San Diego |language=en-US}}</ref> [[Los Cabos International Airport|San José del Cabo]],<ref name=”panrotas.com.br”>{{cite web|url=https://www.panrotas.com.br/aviacao/empresas/2025/07/copa-airlines-anuncia-tres-novas-rotas-para-america-latina_219199.html|title=Copa Airlines anuncia três novas rotas para América Latina|website=Panrotas|date=3 July 2025|access-date=3 July 2025|language=pt}}</ref> [[Cibao International Airport|Santiago de los Caballeros]] (resumes 15 January 2026),<ref name=”panrotas.com.br”>{{cite web|url=https://www.panrotas.com.br/aviacao/empresas/2025/07/copa-airlines-anuncia-tres-novas-rotas-para-america-latina_219199.html|title=Copa Airlines anuncia três novas rotas para América Latina|website=Panrotas|date=3 July 2025|access-date=3 July 2025|language=pt}}</ref> [[Princess Juliana International Airport|Sint Maarten]],<ref>{{OAGWorldJuly2025Ref|title=St. Maarten, St Maarten (Dutch Part) SXM|pages=1000-1000}}</ref> [[Teniente General Benjamín Matienzo International Airport|Tucumán]]{{cn|date=December 2025}}
| {{nowrap|[[Copa Airlines Colombia]]}} | [[Ingeniero Aeronáutico Ambrosio L.V. Taravella International Airport|Córdoba (AR)]]<ref>{{cite web | title=Copa Airlines hará cambios en su operación | date=16 June 2025 | url=https://aviationclubcenter.com/index.php/2025/06/16/copa-airlines-hara-cambios-en-su-operacion/ }}</ref>
| {{nowrap|[[Copa Airlines Colombia]]}} | [[Ingeniero Aeronáutico Ambrosio L.V. Taravella International Airport|Córdoba (AR)]]<ref>{{cite web | title=Copa Airlines hará cambios en su operación | date=16 June 2025 | url=https://aviationclubcenter.com/index.php/2025/06/16/copa-airlines-hara-cambios-en-su-operacion/ }}</ref>
